Page 169 - HPP ANTIMICROBIAL GUIDELINE 2018
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Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Histoplasmosis
Penicilliosis
In less severe: Itraconazole 200mg PO q8h for 3 Immunosuppressed patients.
days, then 200mg q12h for 12 weeks Refer to chapter on HIV
In severe case: Amphotericin B IV 0.6-1mg/kg q24h
for 2 weeks followed with
Itraconazole 400mg q24h for 10 weeks
Viral Infections
Herpes Simplex Infections
Primary Acyclovir 200-400mg PO 5 times daily Valacyclovir 500mg q8h for 10 days Immunosuppressed patients.
for 5 days Refer to chapter on HIV
Genitalia Refer to Sexually Transmitted
Infections-herpes genitalis
Eczema herpeticum Acyclovir 200mg PO 5 times daily for
7-10 days
Severe cases Acyclovir 5mg/kg IV q8h for 5 days or
until able to take orally, then change
to oral
HPP AMG Skin & Soft Tissue Infections 79
