Page 193 - HPP ANTIMICROBIAL GUIDELINE 2018

UROLOGY INFECTIONS
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Pyonephrosis Ampicillin/sulbactam 1.5gm-3gm IV q6h Ceftriaxone 1-2gm IV q24h Drainage followed by definitive
Perinephric abscess surgery is recommended
Renal abscess OR
Amoxicillin/clavulanate 1.2gm IV q8h

Acute prostatitis Ciprofloxacin 400mg IV q12h Trimethoprim/sulfamethoxazole Duration of treatment: 2-4 weeks
(80/400mg) 2 tabs PO q12h

Chronic bacterial prostatitis Ciprofloxacin 400mg IV q12h Trimethoprim/sulfamethoxazole Duration of treatment: 2 weeks
(80/400mg) 2 tabs PO q12h

Prostatic abscess Ciprofloxacin 400mg IV q12h Trimethoprim/sulfamethoxazole Drainage is mandatory
Testicular abscess for 2 weeks (80/400mg) 2 tabs PO q12h

Epididymo-orchitis Doxycycline 100mg PO q12h for 2 weeks. In case of C. trachomatis, the
sexual partner should be treated

Urosepsis Ampicillin/sulbactam 1.5gm-3gm IV q6h Ceftriaxone 1-2gm IV q24h

OR
Amoxicillin/clavulanate 1.2gm IV q8h

References:
1. Guidelines on Urological Infections: 2015.
2. International clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by IDSA
and European Society of Microbiology and Infectious Diseases: 2011:52
3. Diagnosis, Prevention, and Treatment of Catheter Associated Urinary Tract Infection in Adults:2009 International Clinical Practice Guidelines from
the IDSA.

HPP AMG Urology Infections 91