Page 189 - HPP ANTIMICROBIAL GUIDELINE 2018
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URINARY TRACT INFECTIONS
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Acute uncomplicated cystitis **Nitrofurantoin 50-100mg q6h for Trimethoprim/ sulfamethoxazole Duration of treatment should be
5 days (80/400mg) 2 tabs q12h for 3 days. up to 7 days in male
rd
rd
(avoid using in 3 trimester of (avoid using in 3 trimester of pregnancy)
pregnancy) ** avoid in G6PD patient
Acute cystitis in pregnancy Amoxicillin 500mg PO q8h Cefuroxime 500mg PO q12hr for 7 days
Recurrent urinary tract infection Nitrofurantoin 50mg PO nocte for Cephalexin 250mg PO nocte for 3-6
prophylaxis: 3-12months months during pregnancy
>3 episodes/year OR
Trimethoprim/sulfamethoxazole
(80/400mg) 2 tabs PO q24h
for 3-12months
Acute pyelonephritis Ampicillin/sulbactam 3gm IV q6h Ceftriaxone 1-2gm q24h IV Duration 7-10 days
OR
Amoxicillin/clavulanate 1.2gm IV q8h
NATIONALANTIBIOTICGUIDELINE2008
Pregnancy Cefuroxime 750mg IV q8h
HPP AMG Urinary Tract Infections 89
