Page 23 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 23
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
HEPATOBILIARY SURGERY
Open cholecystectomy Ampicillin/sulbactam 3gm IV Cefuroxime 1.5gm IV Antibiotic can be continued for
4-7 days if perforation or
ERCP + stent gallbladder necrosis is
encountered during operation
Laparoscopic cholecystectomy Antibiotic not recommended
GENERAL SURGERY
Upper GIT (oesophagus, stomach & Amoxicillin/clavulanate 1.2gm IV Cefuroxime 1.5gm IV In intestinal obstruction
upper small bowel)
ADD
Metronidazole 500mg IV
Distal small bowel Amoxicillin/clavulanate 1.2gm IV Ceftriaxone 2gm IV
colorectal
PLUS
Metronidazole 500mg IV
Appendectomy procedure Amoxicillin/clavulanate 1.2gm IV Cefuroxime 1.5gm IV
PLUS
Metronidazole 500mg IV
HPP AMG Chemoprophylaxis 6
