Page 25 - HPP ANTIMICROBIAL GUIDELINE 2018

Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Open Hernia repair +/- mesh Amoxicillin/clavulanate 1.2gm IV Cefuroxime 1.5gm IV Laparoscopic hernia +/- mesh
not required SAP

Breast
Mastectomy with axillary clearance Amoxicillin/clavulanate 1.2gm IV Cefuroxime 1.5gm IV Not recommended for minor
with/without reconstruction excisions

only recommended for high risk group

Reference:
1. Dale WB, Patchen D, Keitg MO, Trish MP, Paul GA, Maureen KB, etal. Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. IDSA.
Am J Health-Syst Pharm: 2013; 70:195-283.
2. CS Loozen, K. Kortram, V.N.N. Kornmann, B. van Ramshorst, C.A.J. Knibbe, et al. Randomised Clinical Trial of Extended versus Single-Dose
Perioperative Antibiotive Prophylaxis for Acute Calculous Cholecystitis. Wiley Online Library. 2016.
3. Jashvant Poeran, M.d., Ph. D, Isaac Wasserman, M.P.H., Nicole Zubizarreta, et al. Characteristics of Antibiotic Prophylaxis and Risk of Surgical
Site Infections in Open Colectomies. Disease of The Colon & Rectum Volume 59:8 (2016).
4. Rhiannon JD, MPH, Lillian GD, MD, FACS, Catherine Vick, et al. Choice of Intravenous Antibiotic Prophylaxis for colorectal Surgery Does Matter.
American College of Surgeons. Elsevier; 2013.
5. F. Kockerling, R. Bittner, D. Jacob, C. Schug-Pass, C. Laurenz, D. Adolf, et al. Do We Need Antibiotic Prophylaxis in Endoscopic Inguinal Hernia
Repair? Results of the Herniamed Registry. Surg Endosc (2015) 29: 3741-3749.

HPP AMG Chemoprophylaxis 7