Page 136 - HPP ANTIMICROBIAL GUIDELINE 2018

Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Acute oral pseudomembranous Nystatin (oral suspension) Fluconazole 100mg PO/IV q24h for Gentle oral toilet /oral debridement is
candidiasis 500,000-1,000,000 units q6-8h /day 2 weeks advised
For 1 week
Hyperplastic candidiasis OR Advise patient to maintain good oral
(Candidal leukoplakia) Itraconazole 100mg PO q24h for hygiene
2 weeks

Chronic erythematous candidiasis Local measures- denture cleansers, Nystatin (oral suspension) If acute , advise patient not to wear
(candida-associated denture remove dentures at night 500,000-1,000,000 units q6h-8h denture temporarily for few weeks
stomatitis with or without angular until the candidiasis lesion subsided
chelitis) Soak dentures in chlorhexidine
mouthwash 2% Revise or redo denture

Herpetic gingivostomatitis Symptomatic treatment in most Systemic antiviral
cases. Acyclovir 400-800mg PO 5 times
daily for 7-14 days
Can also consider:
Topical acyclovir 5% cream q4h for OR
5-10 days in prodromal phase for Acyclovir 5mg/kg IV q8h for 5 days
recurrent herpes labialis for severe infection or
immunocompromised patients

REFERENCES:
1. Antibiotics and The Treatment of Endodontic Infections
th
2. Clinical Periodontology-12 ed.2014
3. CPG Management of chronic periodontitis Nov 2012, MOH,Malaysia
4. Eur J Oral Implantol 2012; 5 (Suppl): S21-S41
5. Int.J Oral Maxillofac Implants 2014 (29): 325-34

HPP AMG Oral/ Dental Infections 63