Page 138 - HPP ANTIMICROBIAL GUIDELINE 2018
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OTORHINOLARYNGOLOGY INFECTIONS
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Throat and upper respiratory
Tonsillitis / Pharyngitis Phenoxymethylpenicillin (Pen-V) Amoxicillin 500mg PO q8h Antibiotics should be
500mg PO q12h for 7 days prescribed in
Penicillin Allergy: suspected/proven bacterial
Severe: Azithromycin 500mg PO q24h for infections.
Amoxicillin/clavulanate 1.2gm IV q8h 3-5 days
Acute peritonsillar abscess Ampicillin/sulbactam 3gm IV q6h Severe case: Oral regimen can be given in
Piperacillin/tazobactam 4.5gm IV q8h mild disease.
Abscess need to be drained
Diphtheria Antitoxin Antitoxin
PLUS PLUS
Erythromycin lactobionate 500mg IV q6h Benzylpenicillin 2-4 MU IV q4-6h
followed by erythromycin ethylsuccinate followed by Pen V 250mg PO q6h total of
800mg PO q12h for total of 14 days 14 days
Acute Epiglottitis Ampicillin/sulbactam 3gm IV q6h Ceftriaxone 2gm IV q24h Urgent hospitalisation
Deep Neck Space Abscess Ampicillin/sulbactam 3gm IV q6h Cefuroxime 1.5gm IV q8h Duration: 10-14 days
PLUS
Metronidazole 500mg IV q6h
HPP AMG Otorhinolaryngology Infections 64
