Page 161 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 161

Suggested Treatment
 Infection/ Condition                              Comments
 Preferred       Alternative

 Mycobacterial Infections


 Hansen’s Disease (Leprosy)
 (in non-HIV & HIV patient)
 Paucibacillary   Rifampicin 600mg PO monthly   Bacterial resistance or hypersensitivity  Remarks: Second line can
       to first line                       only be initiated by a
    PLUS   Can be substituted with one of the   dermatologist
    Dapsone 100mg PO q24h   following:

    Duration: 6 months   Ofloxacin 200mg PO q12h
    (Completion of 6 doses within 9
    months)   PLUS
    Surveillance: 5 years
       Minocycline 100mg q24h
       OR
 Multibacillary   Rifampicin 600mg PO monthly   Clarithromycin 500mg PO q12h
       OR
 PLUS   Ethionamide 250mg PO q24h
 Clofazimine 300mg PO monthly

 PLUS
 Dapsone 100mg PO q24h

 PLUS
 Clofazimine 50mg PO q24h

 Duration: 1 year (if initial BI˂4) or  18
 months (if BI≥4)
 Completion of 12 doses within 18
 months (BI<4)
 Completion of 18 doses within 24
 months ( BI≥4)
 Surveillance: 15 years




 HPP AMG    Skin & Soft Tissue Infections                            75
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