Page 177 - HPP ANTIMICROBIAL GUIDELINE 2018

Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Breast abscess Cloxacillin 1gm IV q6h Cefazolin 2gm IV q8h Drainage maybe required

Burn wound sepsis Piperacillin/tazobactam 4.5gm IV Cefepime 1 -2gm IV q8h
q6-8h

Mycotic aneurysm
Vascular prosthesis infection Ampicillin/sulbactam 3gm IV q6h

OR
Amoxicillin/clavulanate 1.2gm IV q8h

If colonized MRSA Vancomycin 25mg/kg IV stat then
1gm q12h

Ischaemic ulcers with infection Ampicillin/sulbactam 1.5gm- 3gm IV Duration of treatment: 7 days
q6h

OR
Amoxicillin/clavulanate 1.2gm IV q8h

Animal or human bite Amoxicillin/clavulanate 1.2gm IV q8h Surgical debridement if necessary

Duration of treatment: 3-5 days

Reference:
1. IDSA Practise Guideline, April 2014
2. The Surgical Infection Society Revised Guidelines on the Management of Intra-abdominal infection: Volume 18, Number 1, 2017

HPP AMG Surgical Infections 83