Page 178 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 178
TROPICAL INFECTIONS
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Typhoid Fever
Salmonella typhi Ampicillin 2gm q6h for 7-14 days Ciprofloxacin 400mg IV q12h for Complicated cases will need
Fully sensitive 7-10 days dexamethasone
dose: 3mg/kg loading, then 1mg/kg
OR q6h for 2 days
Ciprofloxacin 750mg PO q12h for
7-10 days (if able to take orally)
Indication of dexamethasone:
Typhoid psychosis
Quinolone resistance Ceftriaxone 2gm IV q24h 7-14 days Azithromycin 1gm PO loading, then
500mg q24h for 5-7 days
Cholera
Non tetracycline resistance Doxycycline 300mg PO stat Ciprofloxacin 1gm PO stat Principle of treatment:
(once patient can take orally)
Rehydration ORS if tolerating orally
Tetracycline resistance Azithromycin 1gm PO stat Ciprofloxacin 1gm PO stat Monitor urine output
Avoid antidiarrheal agents
Antibiotic therapy for severe cases
Scrub Typhus Doxycycline 100mg PO q12h for Azithromycin 500mg PO stat Recommended alternative for
7 days pregnant woman
HPP AMG Tropical Infections 84
