Page 246 - HPP ANTIMICROBIAL GUIDELINE 2018

OTORHINOLARYNGOLOGY INFECTIONS

Infection/Condition Suggested Treatment Comments
Preferred Alternative

Tonsillitis/Pharyngitis Penicillin allergy:
Group A streptococcal Phenoxymethylpenicillin 25-50mg/kg/day in Azithromycin 12 mg/kg PO q24h for 5 days
4 divided doses PO x 10 days

OR
OR Clarithromycin 7.5mg/kg/dose q12h for 10
Amoxicillin 25 mg/kg q8h or 25-40mg/kg days
q12h PO (max 500mg) for 10 days

Rhinosinusitis
Streptococcus pneumonia Amoxicillin 90mg/kg/day in 2 divided doses or Risk for antibiotic resistance or failed Antibiotic therapy for acute
Haemophilus influenza for 10-14 days initial therapy: bacterial sinusitis in children
Moraxella catarrhalis Amoxicillin/clavulanate 90mg/kg/day in with severe onset or
2 divided doses for 10-14 days worsening course, of high
grade fever, purulent nasal
Severe infection: Ampicillin/sulbactam 200–400 mg/kg/day IV Penicillin allergy: discharge.
q6h Clindamycin 30-40mg/kg/day in 3-4 divided
doses for 10-14 days
OR
Ceftriaxone 50 mg/kg/day IV q12h

HPP AMG Otorhinolaryngology Infections 118