Page 250 - HPP ANTIMICROBIAL GUIDELINE 2018
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RESPIRATORY INFECTIONS

                        Infection/Condition                                Suggested Treatment                                      Comments
                                                               Preferred                         Alternative

                 Community Acquired Pneumonia
                 Outpatient                        Amoxicillin 45-75mg/kg/24h PO q8h   Erythromycin                      Macrolide antibiotics should be used
                                                   for 5-7 days                       Azithromycin                       if either mycoplasma or chlamydia
                                                                                      Clarithromycin                     pneumonia is suspected.
                                                                                                                         It may be added at any age if there
                                                                                                                         is no response to first-line empirical
                 Inpatient                         Benzylpenicillin  30-60mg/kg  IV  q6h                                 therapy.
                                                   for 7 days
                                                                                                                         Azithromycin 15mg/kg IV loading
                                                                                                                         dose then 7.5mg/kg q24h if
                                                                                                                         considering atypical organisms.
                 Severe community acquired         Ceftriaxone 50mg/kg q12h           Cefuroxime 50mg/kg IV q8h
                                                                                                                         Investigate for TB if clinically
                                                   PLUS                                                                  indicated
                                                   Cloxacillin 50mg/kg IV q6h
                                                   (if suspected Staphylococcus
                                                   aureus)







               References:
                   1.  Empiric Antibiotic Guidelines- Sydney Childrens Hospital 2012
                   2.  The Management of Community-Acquired Pneumonia in Infants and Children Older Than 3 Months of Age: Clinical Practice Guidelines by the Pediatric
                       Infectious Diseases Society and the Infectious Diseases Society of America  Clinical Infectious Diseases 2011;53(7):e25–e76
                   3.  Paediatric Protocols For Malaysian Hospitals 3 st     Edition 2012  Ministry Of Health Malaysia
                   4.  Drug Doses  Frank Shann 15 th  edition.






               HPP AMG                                                     Respiratory Infections                                                       120
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