Page 30 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 30

Suggested Treatment
                           Infection/ Condition                                                                                       Comments
                                                                     Preferred                        Alternative

                 NEUROLOGICAL SURGERY


                 Clean +/- implant                        Cefazolin 2gm IV                 Cefuroxime 1.5gm IV              MRSA colonisation:
                                                                                                                            Vancomycin 15mg/kg IV
                 Clean contaminated


                 Reference:
                    1.  Peter MV, MD, MSPH, Joseph Zen  ga, Ryan SJ.  Antibiotic Prophylaxis in Clean-Contaminated Head and Neck Surgery: A  Systemic Review and
                        Meta-analysia.  American Academy of Otolaryngology- Head and Neck Surgery Foundation 2017.
                    2.  Michael PV, Susan LD, Amy MW, John EM, Tamer AG. Considerations for Antibiotic Prophylaxis in head and Neck Cancer Surgery.  2017.


                 CARDIAC SURGERY


                 Cardiac surgery                          Cefazolin 2gm IV                 Amoxicillin/clavulanate 1.2gm IV    MRSA colonisation:
                                                                                                                            Vancomycin 15mg/kg IV


                 Reference:
                    1.  Fathima Paruk, Fekade BS, Jefferey Lipman, Jason AR.  Dosing Antibiotic Prophylaxis Cardiopulmonary Bypass-A higher Level of  Complexity? A
                        Structured Review.  International Journal of Antimicrobial Agents.  2017.


                 OPHTHALMOLOGY

                 Subconjunctival cefazolin 1mg at the end of procedure Intracameral injection of 1mg Cefuroxime in 0.1ml at the end of cataract surgery is recommended.
                 Careful dilution should be undertaken to prevent potential toxicity

                 Reference:
                    1.  Lisa JH, Neal HS, MD, John FP, Liyan Liu, Richard C, et al.  Comparative Effectiveness of Antibiotic Prophylaxis in Cataract Surgery.  American
                        Academy of Ophthalmology.  2016; pg 226.




               HPP AMG                                                       Chemoprophylaxis                                                            10
   25   26   27   28   29   30   31   32   33   34   35