Page 279 - HPP ANTIMICROBIAL GUIDELINE 2018

Infection/Condition Suggested Treatment Comments
Preferred Alternative

Suppurative thrombophlebitis

S. aureus
MSSA Cloxacillin 100-200mg/kg/day IV q6h Diagnosis require positive blood culture plus
radiographic demonstration of thrombus.

MRSA Vancomycin 10-15 mg/kg/day IV q6h Removed catheter and minimum of 3-4
weeks of antibiotics.

Surgical resection of involved vein if failed
conservative therapy

References:
1. IDSA Guidelines for Intravascular Catheter-Related Infection • CID 2009;49:1-45
2. Patricia MF. Diagnosis and Management of Central-Venous Catheter-Related Bloodstream Infections in Pediatric Patients. Paediatric Infect Dis J.
2009;28(11):1016-1017
3. Michael JS, Catheter Related Bloodstream Infection In Children. Am J Infect Control 2008;36:S173.e1-S173.e3.

HPP AMG Vascular Infections 134