Page 34 - HPP ANTIMICROBIAL GUIDELINE 2018

Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Prophylactic regime for dental, oral, Amoxicillin 2gm PO single dose Ampicillin 2gm IV single dose 1 hour
respiratory tract, skin and 1 hour before procedure before procedure
musculoskeletal tissue

Secondary prevention of Benzathine penicillin G 1.2 MU IM Penicillin V 250mg PO q12h
rheumatic fever every 3 weeks

References:
nd
1. The Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease (2 edition)
2. Antimicrobial prophylaxis for the prevention of bacterial endocarditis. UpToDate.

Type of Infection Duration of treatment

Rheumatic fever with carditis and residual heart disease 10 years or until 40 years of age, whichever is longer;
(persistent valvular disease) sometimes need lifelong prophylaxis

Rheumatic fever with carditis but no residual heart disease 10 years or until 21 years of age, whichever is longer
(no valvular disease)

Rheumatic fever without carditis 5 years or until 21 years of age, whichever is longer

HPP AMG Chemoprophylaxis 12