Page 35 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 35

Suggested Treatment
 Infection/ Condition                           Comments
 Preferred   Alternative

 Prophylactic regime for dental, oral,  Amoxicillin 2gm PO single dose    Ampicillin 2gm IV single dose 1 hour
 respiratory tract, skin and   1 hour before procedure   before procedure
 musculoskeletal tissue


 Secondary prevention of    Benzathine penicillin G 1.2 MU IM   Penicillin V 250mg PO q12h
 rheumatic fever   every 3 weeks


 References:
                                                  nd
 1.  The Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease (2  edition)
 2.  Antimicrobial prophylaxis for the prevention of bacterial endocarditis.  UpToDate.






 Type of Infection       Duration of treatment

 Rheumatic fever with carditis and residual heart disease    10 years or until 40 years of age, whichever is longer;
 (persistent valvular disease)   sometimes need lifelong prophylaxis


 Rheumatic fever with carditis but no residual heart disease    10 years or until 21 years of age, whichever is longer
 (no valvular disease)


 Rheumatic fever without carditis   5 years or until 21 years of age, whichever is longer











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