Page 105 - HPP ANTIMICROBIAL GUIDELINE 2018
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OBSTETRICS & GYNAECOLOGICAL INFECTIONS
Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Septic Abortion Ampicillin 2gm IV q4h Ampicillin/sulbactam 3gm IV q6h To complete a 10-14 days
PLUS PLUS
Gentamicin 5mg/kg IV q24h Doxycycline 100mg PO q12h
PLUS OR
Metronidazole 500mg IV q8h
Clindamycin 900mg IV q8h
PLUS
Gentamicin 5mg/kg IV q24h
Intrapartum antibiotic Penicillin G 5MU IV initial dose, Ampicillin 2gm IV initial dose, then Prophylaxis should be started at
prophylaxis(IAP) then 2.5 – 3MU IV q4h until delivery 1gm IV q4h until delivery. labour or rupture of membranes
for Group B Strep. positive mothers and continued every four hours
until the infant is delivered.
Preterm Premature Rupture of
Membranes (PPROM)
If non-GBS carrier: Erythromycin ethylsuccinate (EES)
400mg PO q12h for 7-10 days
If GBS carrier: Ampicillin 2gm IV q6h for 48 hours
followed by
Amoxicillin 500mg PO q8h for an
additional 5-7 days or until delivery
(whichever comes first)
PLUS
Azithromycin 1gm PO one dose
HPP AMG Obstetrics & Gynaecological Infections 47
