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Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Fungal Keratitis **Natamycin 5% eye drop q1-2h ***Voriconazole 1% eye drop q1-2h *Prepared ready to use
extemporaneously by injectable
OR OR forms
*Amphotericin B 0.15%-0.2% eye *Fluconozole 0.2% eye drop q1-2h
drop q1-2h **Requires DG approval
Oral Therapy
May be considered in the absence NATIONAL ANTIBIOTIC GUIDELINE 2008
of contraindications .
Fluconazole 200mg PO q24h
OR
Ketoconazole 200mg POq24h
Herpes Simplex Keratitis
Herpes Simplex Type 1 & 2 Acyclovir 3% eye ointment
5 times/day
In presence of stromal or Acyclovir 400mg PO 5 times/day
endothelial disease 7-14 days
Prophylaxis for recurrent cases: Acyclovir 400mg PO q12h for
12 months
HPP AMG Ocular Infections 53
