Page 120 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 120

Suggested Treatment
                       Infection/ Condition                                                                                         Comments
                                                              Preferred                          Alternative

                 CMV Retinitis                    Ganciclovir  5mg/kg IV q12h  for    ** Valganciclovir: 900mg PO q12h    Maintenance may need to continue
                                                  2-3 weeks                          for 3 weeks  ( induction) followed by   until CD4 count is >150 cells/mm3 for
                                                                                     900mg PO q24h (maintenance)        3 consecutive months
                                                  PLUS
                                                  Intravitreal ganciclovir 2mg/0.1ml   Intravitreal **Foscarnet 2.4mg/0.1ml
                                                  biweekly                           (1-2weekly)                        Intravitreal therapy is indicated in
                                                                                                                        zone 1 and 2 lesions.


                                                                                                                        Ganciclovir implant: 4.5gm an option
                                                                                                                        for prolonged usage of intravitreal
                                                                                                                        ganciclovir


                                                                                                                        **Requires DG approval



                 Ocular Syphilis                  Ocular Syphilis ( syphilitic uveitis)                                 Referral to Dermatologist/ID
                                                  should be treated as Neurosyphilis                                    Physician
                                                  Refer to Sexually Transmitted
                                                  Infections Section
















               HPP AMG                                                        Ocular Infections                                                          55
   115   116   117   118   119   120   121   122   123   124   125