Page 200 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 200

Haemophilus influenza b

               Close (household) contact is defined as a person who resides with the index patient or who spent ≥4 hours with the index patient for at least five
               of the seven days before the day of hospital admission of the index case


               Household contacts

               • Household with at least one contact <4 years who has not received an age-appropriate number of doses of Hib conjugate vaccine
               • Household with a contact who is an immunocompromised child (<18 years), regardless of that child's Hib immunization status

               Nursery Contact

                For child-care and preschool contacts (regardless of age or vaccine status) when unimmunized or incompletely immunized children attend the
               facility and two or more cases of Hib invasive disease have occurred among attendees within 60 days


               Give chemoprophylaxis to index case if treated with regimens other than cefotaxime or ceftriaxone

               For Contacts < 2 years not immunized: complete immunization


                                                                  Suggested Treatment
                   Infection/Condition                                                                                          Comments
                                                        Preferred                         Alternative

                 Haemophilus influenza b   Rifampicin PO
                 Close contacts
                                          Children:
                                          20mg/kg/day q24h for 4 days

                                          Infants:
                                          10mg/kg/day q24h for 4 days






               HPP AMG                                                       Chemoprophylaxis                                                            95
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