Page 201 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 201

Haemophilus influenza b

 Close (household) contact is defined as a person who resides with the index patient or who spent ≥4 hours with the index patient for at least five
 of the seven days before the day of hospital admission of the index case


 Household contacts

 • Household with at least one contact <4 years who has not received an age-appropriate number of doses of Hib conjugate vaccine
 • Household with a contact who is an immunocompromised child (<18 years), regardless of that child's Hib immunization status

 Nursery Contact

  For child-care and preschool contacts (regardless of age or vaccine status) when unimmunized or incompletely immunized children attend the
 facility and two or more cases of Hib invasive disease have occurred among attendees within 60 days


 Give chemoprophylaxis to index case if treated with regimens other than cefotaxime or ceftriaxone

 For Contacts < 2 years not immunized: complete immunization


 Suggested Treatment
 Infection/Condition                        Comments
 Preferred   Alternative

 Haemophilus influenza b   Rifampicin PO
 Close contacts
 Children:
 20mg/kg/day q24h for 4 days

 Infants:
 10mg/kg/day q24h for 4 days






 HPP AMG   Chemoprophylaxis                                          95
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