Page 203 - HPP ANTIMICROBIAL GUIDELINE 2018

Meningococcal exposure

CLOSE contact defined as individuals who have had prolonged (>8 hours) contact while in close proximity (<3 ft) to the patient or who have been
directly exposed to the patient's oral secretions during the seven days before the onset of the patient's symptoms and until 24 hours after initiation
of appropriate antibiotic therapy:

All household, child care and nursery, school contacts

Others
• Close contact for at least 4 hours during the week before illness onset

• Exposure to index’s nasopharyngeal secretions (eg kissing, sharing of toothbrushes, eating utensils)

• Airline flights lasting >8 hours: directly next to case
Healthcare staff

Routine prophylaxis not recommended, unless exposure to secretions such as unprotected mouth to mouth resuscitation, intubation or suctioning

Suggested Treatment
Infection/Condition Comments
Preferred Alternative

Meningococcal exposure Rifampicin PO Ceftriaxone IM
<15 yo : 125mg stat
Children: >15 yo : 250mg stat
<1 month: 5mg/kg/dose q12h for 2 days
>1 month: 10mg/kg/dose (max 600mg) Ciprofloxacin PO
q12h for 2 days >18 yo: 500mg single dose

HPP AMG Chemoprophylaxis 96