Page 212 - HPP ANTIMICROBIAL GUIDELINE 2018
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CARDIOVASCULAR INFECTIONS

                       Infection/Condition                                  Suggested Treatment                                       Comments
                                                                Preferred                           Alternative

                Acute myocarditis                  Treatment mainly supportive
                Commonly caused by viruses


                Acute pericarditis                 Treatment mainly supportive                                               Consider surgical drainage if
                Viral (commonest cause)                                                                                      pericardial empyema detected

                Bacterial:                         Cloxacillin 200 mg/kg/24h IV q4-6h   Penicillin Allergic:
                Staphylococcus aureus              for 6 weeks                          Cefazolin 100 mg/kg/24h IV q8h

                                                   PLUS/MINUS                           OR
                                                   Gentamicin 1 mg/kg IV/IM q8h for 3 -  Vancomycin 40 mg/kg/24h IV in 2-4
                                                   5 days                               divided doses


                Infective Endocarditis


                Empirical therapy                  Benzylpenicillin 200,000-300,000     Vancomycin 15 mg/kg q12h IV for 4-6
                                                   units/kg/24h IV q4-6h for 4 weeks    weeks

                                                   PLUS                                 PLUS


                                                   Gentamicin 1 mg/kg IV/IM q8h for 2   Gentamicin 1 mg/kg IV/IM q8h for 2
                                                   weeks                                weeks











            HPP AMG                                                       Cardiovascular Infection                                                         101
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