Page 213 - HPP ANTIMICROBIAL GUIDELINE 2018
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CARDIOVASCULAR INFECTIONS

 Infection/Condition   Suggested Treatment       Comments
 Preferred     Alternative

 Acute myocarditis   Treatment mainly supportive
 Commonly caused by viruses


 Acute pericarditis   Treatment mainly supportive      Consider surgical drainage if
 Viral (commonest cause)                pericardial empyema detected

 Bacterial:   Cloxacillin 200 mg/kg/24h IV q4-6h   Penicillin Allergic:
 Staphylococcus aureus   for 6 weeks   Cefazolin 100 mg/kg/24h IV q8h

 PLUS/MINUS   OR
 Gentamicin 1 mg/kg IV/IM q8h for 3 -  Vancomycin 40 mg/kg/24h IV in 2-4
 5 days   divided doses


 Infective Endocarditis


 Empirical therapy    Benzylpenicillin 200,000-300,000   Vancomycin 15 mg/kg q12h IV for 4-6
 units/kg/24h IV q4-6h for 4 weeks   weeks

 PLUS   PLUS


 Gentamicin 1 mg/kg IV/IM q8h for 2   Gentamicin 1 mg/kg IV/IM q8h for 2
 weeks   weeks











 HPP AMG   Cardiovascular Infection                                    101
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