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CARDIOVASCULAR INFECTIONS
Infection/Condition Suggested Treatment Comments
Preferred Alternative
Acute myocarditis Treatment mainly supportive
Commonly caused by viruses
Acute pericarditis Treatment mainly supportive Consider surgical drainage if
Viral (commonest cause) pericardial empyema detected
Bacterial: Cloxacillin 200 mg/kg/24h IV q4-6h Penicillin Allergic:
Staphylococcus aureus for 6 weeks Cefazolin 100 mg/kg/24h IV q8h
PLUS/MINUS OR
Gentamicin 1 mg/kg IV/IM q8h for 3 - Vancomycin 40 mg/kg/24h IV in 2-4
5 days divided doses
Infective Endocarditis
Empirical therapy Benzylpenicillin 200,000-300,000 Vancomycin 15 mg/kg q12h IV for 4-6
units/kg/24h IV q4-6h for 4 weeks weeks
PLUS PLUS
Gentamicin 1 mg/kg IV/IM q8h for 2 Gentamicin 1 mg/kg IV/IM q8h for 2
weeks weeks
HPP AMG Cardiovascular Infection 101