Page 265 - HPP ANTIMICROBIAL GUIDELINE 2018

TROPICAL INFECTIONS

Infection/Condition Suggested Treatment Comments
Preferred Alternative

Typhoid fever Refer to Gastrointestinal infections Section

Cholera Refer to Gastrointestinal infections Section

Scrub Typhus For children > 8 yr: Azithromycin 10mg /kg PO q24h for 5 days Avoid using tetracycline
Ricketsia tsutsugamushi Doxycycline 2-4mg/kg/24h q12-24h for 5-7 days or doxycycline for
young children as they
can cause staining of
the teeth

Brucellosis For children < 8 yr:
B. melitensis, Trimethoprim(TMP) / Sulfamethoxazole Trimethoprim(TMP)/ sulfamethoxazole TMP For children > 8 yr:
B. abortus, B. suis and TMP 8-10mg /kg/24h PO q12h for 6 weeks 8-10mg/kg/24h PO q12h for6 weeks Refer adult regime
B. canis
PLUS PLUS
Streptomycin 30 mg/kg (max 1gm) IM q24h Rifampicin 15-20mg/kg PO q24h for 6 weeks

OR
Gentamicin 5mg/kg IV q24h
for 3 weeks

HPP AMG Tropical Infections 127