Page 253 - HPP ANTIMICROBIAL GUIDELINE 2018
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SKIN & SOFT TISSUE INFECTIONS
Infection/Condition Suggested Treatment Comments
Preferred Alternative
Abscess Incision & drainage if indicated. Send
Staphylococcus aureus Cloxacillin 100-200mg/ kg/24h PO/IV pus for culture.
q6h for 7-10 days
Parenteral route for severe infections.
Consider CA-MRSA if poorly resolving ,
based on local epidemiology.
Animal bites
Pasteurella multocida, Amoxicillin/clavulanate 25-30mg/kg PO Ampicillin/sulbactam 50 mg/kg Consider rabies prophylaxis according
Staphy. spp, Streptococcus oral (ampicillin component) IV q6h for 7 to local epidemiology
spp , Capnocytophaga, days
anaerobes
Severe:
Amoxicillin/clavulanate 50mg/kg IV
(amoxicillin component) for 7 days
Cellulitis Cloxacillin 25-50mg/ kg IV or 15mg/kg Amoxicillin 25-30mg/kg PO q8h for 7 Parenteral route for extensive lesions
Staphylococcus aureus PO q6h for 7-10 days days
Streptococcus pyogenes
OR
Cephalexin 12.5mg/kg PO q6h for 7
days
HPP AMG Skin & Soft Tissue Infections 121
