Page 255 - HPP ANTIMICROBIAL GUIDELINE 2018
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Infection/Condition Suggested Treatment Comments
Preferred Alternative
Hansen’s Disease (Leprosy)
Paucibacillary 10-14 years
Rifampicin 450mg PO monthly Duration: 6 months
Surveillance: 5 years
PLUS
Dapsone 50mg PO q24h
˂10 years
Rifampicin 10mg/kg PO monthly
PLUS
Dapsone 2mg/kg PO q24h
Multibacillary 10-14 years
Rifampicin 450mg PO monthly Duration:
1 year for BI ˂ 4 and
PLUS 2 years for BI ≥ 4
Dapsone 50mg PO q24h Surveillance: 15 years
PLUS
Clofazimine 150mg PO monthly and
50mg EOD
˂10 years
Rifampicin 10mg/kg PO monthly
PLUS
Dapsone 2mg/kg PO q24h
PLUS
Clofazimine 6mg/kg PO monthly and
1mg/kg EOD
HPP AMG Skin & Soft Tissue Infections 122
