Page 254 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 254

Infection/Condition                              Suggested Treatment                                          Comments
                                                          Preferred                           Alternative

                 Hansen’s Disease (Leprosy)
                 Paucibacillary              10-14 years
                                             Rifampicin 450mg PO monthly                                              Duration: 6 months
                                                                                                                      Surveillance: 5 years
                                             PLUS
                                             Dapsone 50mg PO q24h

                                             ˂10 years
                                             Rifampicin 10mg/kg PO monthly

                                             PLUS
                                             Dapsone 2mg/kg PO q24h


                 Multibacillary              10-14 years
                                             Rifampicin 450mg PO monthly                                              Duration:
                                                                                                                      1 year for BI ˂ 4 and
                                             PLUS                                                                     2 years for BI ≥ 4
                                             Dapsone 50mg PO q24h                                                     Surveillance: 15 years

                                             PLUS
                                             Clofazimine 150mg PO monthly and
                                             50mg EOD

                                             ˂10 years
                                             Rifampicin 10mg/kg PO monthly

                                             PLUS
                                             Dapsone 2mg/kg PO q24h

                                             PLUS
                                             Clofazimine 6mg/kg PO monthly and
                                             1mg/kg EOD





               HPP AMG                                                   Skin & Soft Tissue Infections                                                  122
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