Page 70 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 70

GASTROINTESTINAL INFECTIONS
                                                                             Suggested Treatment
                      Infection/ Condition                                                                                             Comments
                                                                Preferred                              Alternative

                 Oropharyngeal Candidiasis
                 Mild                            Nystatin suspension 500 000 units PO q6h    Itraconazole 200mg PO q24h        Duration: 7-14 days

                 Moderate to severe              Fluconazole 100-200mg PO q24h


                 Candida Esophagitis             Fluconazole 200-400mg PO q24h            Itraconazole 200mg PO q24h           Duration: 14 days


                 Herpes simplex virus
                 Immunocompetent host            Acyclovir 400mg PO q8h for 7 days

                 Immunocompromised host          Acyclovir 400mg PO q8h for 14 days



                 Helicobacter pylori             *Proton Pump Inhibitors(PPI) PO          Recurrence of H.pylori disease/      Duration: 14 days
                                                                                          macrolide exposure
                                                 PLUS                                     Avoid antibiotics that have been
                                                 Clarithromycin 500mg PO q12h             previously taken.

                                                 PLUS
                                                 Amoxicillin 1gm PO q12h

                                                 OR
                                                 Metronidazole 400mg PO q12h
                                                 (if penicillin allergy)



                 References:
                 1.  American College of Gastroenterology guideline: Treatment of Helicobacter pylori Infection 2017; 112:212-238





               HPP AMG                                                   Gastrointestinal Infections                                                     30
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