Page 71 - HPP ANTIMICROBIAL GUIDELINE 2018
P. 71

GASTROINTESTINAL INFECTIONS
 Suggested Treatment
 Infection/ Condition                              Comments
 Preferred         Alternative

 Oropharyngeal Candidiasis
 Mild   Nystatin suspension 500 000 units PO q6h    Itraconazole 200mg PO q24h    Duration: 7-14 days

 Moderate to severe   Fluconazole 100-200mg PO q24h


 Candida Esophagitis   Fluconazole 200-400mg PO q24h    Itraconazole 200mg PO q24h    Duration: 14 days


 Herpes simplex virus
 Immunocompetent host   Acyclovir 400mg PO q8h for 7 days

 Immunocompromised host   Acyclovir 400mg PO q8h for 14 days



 Helicobacter pylori   *Proton Pump Inhibitors(PPI) PO     Recurrence of H.pylori disease/    Duration: 14 days
       macrolide exposure
 PLUS   Avoid antibiotics that have been
 Clarithromycin 500mg PO q12h    previously taken.

 PLUS
 Amoxicillin 1gm PO q12h

 OR
 Metronidazole 400mg PO q12h
 (if penicillin allergy)



 References:
 1.  American College of Gastroenterology guideline: Treatment of Helicobacter pylori Infection 2017; 112:212-238





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