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Suggested Treatment
Infection/ Condition Comments
Preferred Alternative

Travellers’ diarrhoea Azithromycin 1gm PO single dose Ciprofloxacin 750mg PO single dose

References:
1. Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2017 Update by the Society for Healthcare Epidemiology of America
(SHEA) and the Infectious Diseases Society of America (IDSA)
2. Practice Guidelines for the Diagnosis and Management of Infectious Diarrhoea, IDSA GUIDELINES ,2017

Pyogenic liver abscess Ampicillin/sulbactam 3gm IV q6h Metronidazole 500mg IV q8h Duration : 4-6 weeks

PLUS Abscess drainage is the
Ceftriaxone 1-2gm IV q24h optimal therapy.

Amoebic liver abscess Metronidazole 800mg PO q8h Duration: 7-10 days
Entamoeba histolytica

References:
1. John Hopkins antibiotics guide: Hepatic Abscess. October 4, 2017.

Cholecystitis and Cholangitis Amoxicillin/clavulanate 1.2gm IV q8h Ceftriaxone 2gm IV q24h No need antibiotic if the
obstruction is relieved.
OR PLUS
Ampicillin/sulbactam 3gm IV q6h Metronidazole 500mg IV q6h Complicated with sepsis :
4-7 days, if source control is
achieved.

References:
1. Gastroenterology & hepatology: Management of Acute Cholangitis. 2011 Feb: 7(2);121-123

HPP AMG Gastrointestinal Infections 33