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Suggested Treatment
Infection/ Condition Comments
Preferred Alternative
Spontaneous bacterial peritonitis (SBP)
Primary SBP Cefotaxime 2gm IV q8h for 5-7 days Ceftriaxone 2gm IV q24h for 5-7 days Duration of therapy: 2 weeks
if blood culture positive.
SBP Prophylaxis Ceftriaxone 1 gm IV q24h Cefotaxime 2gm IV q24h Duration: 5-7 days
Recurrent SBP Ciprofloxacin 750mg PO per week
References:
1. Management of Ascites, Spontaneous Bacterial Peritonitis in Cirrhosis, Journal of Hepatology, 2010: volume 53, no3
CAPD Peritonitis Intra peritoneal Cefazolin 15 mg/kg per bag Consider catheter removal in
once daily relapsing or refractory
peritonitis and for fungal
PLUS peritonitis.
Intra peritoneal Ceftazidime 1-1.5gm per
bag once daily
HPP AMG Gastrointestinal Infections 34
